Imagine sealing yourself in giant, glass, self-contained ecosystem with your boyfriend and a lady who's learning to play saxophone... for TWO YEARS. In 1991, eight semi-qualified volunteers entered Biosphere 2, and promised that they would live inside the giant science experiment without any help from the outside. However, thanks to chopped off fingers, oxygen-gulping bacteria, rampant cockroaches and Steve Bannon, Biosphere 2 would become one of the biggest scientific flops in history.

Alie Ward (In the Wild, Oologies) and Josh Gondelman (Last Week Tonight, Modern Seinfeld) join Misha for this failed science experiment gone too far.

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